The application of bioimplants in the management of chronic osteomyelitis.

Wang, Jue; Calhoun, Jason H; Mader, Jon T · Orthopedics · 2002

review · Level V

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Abstract

The management of musculoskeletal infections is an increasing challenge to clinicians. Bioimplants provide a unique system for skeletal specific drug delivery. Antibiotic-impregnated beads and spacers can be used to treat chronic osteomyelitis and deep soft-tissue infections locally with higher antibiotic concentrations, while avoiding potential systemic side effects.

Medical subject headings