How to flip the (redox) switch.
review · Level V
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- Record sourced from PubMed, PMID 12464172.
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Abstract
Redox-sensitive transcription factors such as the E. coli OxyR and S. cerevisiae Yap1, are activated by conformational changes that stem from the post-translational modification of reactive protein thiols. Recent studies provide new insights on how different agents that cause redox stress mediate the activation of transcription through distinct and specific pathways.
Medical subject headings
- Bacterial Proteins
- Escherichia coli
- Oxidation-Reduction
- Saccharomyces cerevisiae
- Transcription Factors