The poly(A) tail of mRNAs: bodyguard in eukaryotes, scavenger in bacteria.
review · Level V
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Abstract
In eukaryotes, poly(A) tails usually act as stabilizers of intact mRNAs, whereas in E. coli they serve to accelerate the destruction of fragments. The mechanisms underlying these contrasting effects of the same RNA modification are discussed.
Medical subject headings
- Escherichia coli
- Eukaryotic Cells
- Poly A
- RNA, Messenger