OWEN: aligning long collinear regions of genomes.
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- Record sourced from PubMed, PMID 12490463.
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Abstract
OWEN is an interactive tool for aligning two long DNA sequences that represents similarity between them by a chain of collinear local similarities. OWEN employs several methods for constructing and editing local similarities and for resolving conflicts between them. Alignments of sequences of lengths over 10(6) can often be produced in minutes. OWEN requires memory below 20 L, where L is the sum of lengths of the compared sequences.
Medical subject headings
- Algorithms
- Genome
- Sequence Alignment
- Sequence Analysis, DNA