Detection of hydrogen-bond signature patterns in protein families.
basic_science · Level V
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Abstract
We have developed a WWW server, HBPRINT, for the identification of hydrogen-bond signature patterns in protein families from their structures. The server calculates (a) common hydrogen bonds between two structures (b) a hydrogen-bond fingerprint in a set of structural neighbours and (c) details of conserved hydrogen bonds. The server also enables the visualization of the hydrogen bond network comprising the signature pattern. HBPRINT and a tutorial are available from http://144.16.93.115/hb_page/index.html.
Medical subject headings
- Conserved Sequence
- Proteins
- Sequence Alignment
- User-Computer Interface