Gabapentin in late-onset poststroke seizures.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 12499501.
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Abstract
Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.
Medical subject headings
- Acetates
- Amines
- Anticonvulsants
- Cyclohexanecarboxylic Acids
- Seizures
- Stroke
- gamma-Aminobutyric Acid