A paradoxical ocular effect of brimonidine.
case_report · Level V
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- Record sourced from PubMed, PMID 12504711.
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Abstract
We report an unusual paradoxical effect of brimonidine. Observational case report. A 70-year-old woman with bilateral normal tension glaucoma was treated with topical brimonidine and followed in an outpatient setting. The main outcome measured was intraocular pressure (IOP) in mm Hg. Brimonidine was observed to cause IOP elevation, confirmed on rechallenge, scoring 8 (strong probability) on an adverse drug reaction probability score. Under certain circumstances topical brimonidine can cause paradoxical raised IOP necessitating vigilance in follow-up of patients on topical brimonidine.
Medical subject headings
- Adrenergic alpha-Agonists
- Intraocular Pressure
- Ocular Hypertension
- Quinoxalines