A web of circadian pacemakers.
review · Level V
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- Record sourced from PubMed, PMID 12507418.
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Abstract
The mammalian circadian timing system is composed of almost as many individual clocks as there are cells. These countless oscillators have to be synchronized by a central pacemaker to coordinate temporal physiology and behavior. Recently, there has been some progress in understanding the relationship and communication mechanisms between central and peripheral clocks.
Medical subject headings
- Biological Clocks
- Circadian Rhythm
- Eukaryotic Cells
- Gene Expression Regulation