Osteosarcoma of bone in apatient with primary hyperparathyroidism: a case report.

Betancourt, M; Wirfel, K L; Raymond, A K; Yasko, A W; Lee, J; Vassilopoulou-Sellin, R · J Bone Miner Res · 2003

case_report · Level V

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Abstract

A 69-year-old woman was diagnosed with a malignant tumor of the right proximal femur. She had primary hyperparathyroidism and chronic elevation of parathyroid hormone levels (PTH > 1,000 pg/ml). She underwent resection of the bone lesion; histological analysis showed a high-grade fibroblastic osteosarcoma. In addition, she underwent curative resection of a large left superior parathyroid adenoma. To our knowledge, this is the third reported clinical case of osteosarcoma arising in association with hyperparathyroidism.

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