Pars, PI 3-kinase, and the establishment of neuronal polarity.
basic_science · Level V
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Abstract
As reported in this issue of Cell, the protein complex consisting of mPar3, mPar6, and atypical protein kinase C is selectively localized to the axonal growth cone of cultured hippocampal neurons and is required for specification of the axon.
Medical subject headings
- Cell Polarity
- Neurons
- Phosphatidylinositol 3-Kinases