Controlling calcium entry.
review · Level V
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- Record sourced from PubMed, PMID 12526803.
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Abstract
Ca(2+) enters cells through an assortment of Ca(2+)-permeable channels that respond to different stimuli and couple to different cellular responses. Several different Ca(2+) entry pathways can be activated by receptors that stimulate phospholipase C (PLC). Both limbs of this signaling pathway (IP(3) and diacylglycerol), PLC itself, and its substrate (PIP(2)) contribute to the coordinate regulation of these Ca(2+) entry pathways.
Medical subject headings
- Calcium
- Inositol 1,4,5-Trisphosphate
- Phosphatidylinositol 4,5-Diphosphate
- Type C Phospholipases