Multiple roles of nitric oxide in the airways.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 12554905.
- Also identified by PMC identifier 1746564.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Nitric oxide is endogenously released in the airways by nitric oxide synthase. Functionally, two isoforms of this enzyme exist: constitutive and inducible. The former seems to protect airways from excessive bronchoconstriction while the latter has a modulatory role in inflammatory disorders of the airways such as asthma. This review explores the physiological and pathophysiological role of endogenous nitric oxide in the airways, and the clinical aspects of monitoring nitric oxide in exhaled air of patients with respiratory disease.
Medical subject headings
- Bronchi
- Nitric Oxide
- Respiration Disorders