Knowledge of antiretroviral regimen dosing and adherence: a longitudinal study.

Miller, Loren G; Liu, Honghu; Hays, Ron D; Golin, Carol E; Ye, Zhishen; Beck, C Keith; Kaplan, Andrew H; Wenger, Neil S · Clin Infect Dis · 2003

prospective_cohort · Level II

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Abstract

In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.

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