Evidence of cardiac ischemia during seizures in drug refractory epilepsy patients.

Tigaran, S; Mølgaard, H; McClelland, R; Dam, M; Jaffe, A S · Neurology · 2003

case_series · Level IV

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Abstract

The authors investigated whether patients with drug refractory epilepsy have cardiovascular abnormalities that might be related to a high frequency of sudden death. Twenty-three subjects underwent comprehensive cardiovascular evaluations before and during video-EEG monitoring. ST-segment depression occurred in 40% and was associated with a higher maximum heart rate during seizures. These data suggest that cardiac ischemia may occur in these patients.

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