IgA pemphigus occurring in a 1-month-old infant.
case_report · Level V
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- Record sourced from PubMed, PMID 12582378.
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Abstract
An 11-month-old girl had recurrent pruritic vesiculopustular lesions involving the trunk, extremities, and scalp since the age of 1-month. Histopathologic examination revealed an intraepidermal bulla produced by acantholysis and neutrophilic spongiosis. Direct immunofluorescence showed IgA deposits in the intercellular space throughout the epidermis. Circulating anti-intercellular IgA autoantibodies were absent. Dapsone therapy was effective.
Medical subject headings
- Immunoglobulin A
- Pemphigus