PDP: protein domain parser.
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- Record sourced from PubMed, PMID 12584135.
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Abstract
We have developed a program for automatic identification of domains in protein three-dimensional structures. Performance of the program was assessed by three different benchmarks: (i) by comparison with the expert-curated SCOP database of structural domains; (ii) by comparison with a collection of manual domain assignments; and (iii) by comparison with a set of 55 proteins, frequently used as a benchmark for automatic domain assignment. In all these benchmarks PDP identified domains correctly in more than 80% of proteins. http://123d.ncifcrf.gov/.
Medical subject headings
- Algorithms
- Databases, Protein
- Protein Structure, Tertiary
- Proteins
- Sequence Analysis, Protein