Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology.

Abstract

Our objective was to show the spectrum of biologic behavior associated with breast adenomyoepithelioma. This disease is a rare benign breast neoplasm characterized by proliferation of both epithelial and myoepithelial cellular elements. Malignant change of one or both cell types may occur and is thought to be associated with hematogenous, rather than lymphatic, metastasis. Three patients with benign and malignant adenomyoepithelioma were included in this study. The imaging and histopathologic findings in these three patients are illustrated, and the treatment of patients with this unusual tumor is discussed.