The induction of apoptosis by local anesthetics: a comparison between lidocaine and ropivacaine.

Boselli, Emmanuel; Duflo, Frédéric; Debon, Richard; Allaouchiche, Bernard; Chassard, Dominique; Thomas, Luc; Portoukalian, Jacques · Anesth Analg · 2003

other · Level V

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Abstract

This study suggests that lidocaine can induce apoptosis (detected by dual staining with Annexin V and propidium iodide) on T-cell line cultures in a time-dependent manner. This was not observed with ropivacaine.

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