Paroxysmal cold hemoglobinuria and cardiopulmonary bypass.
case_report · Level V
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- Record sourced from PubMed, PMID 12607681.
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Abstract
Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.
Medical subject headings
- Cardiopulmonary Bypass
- Heart Arrest, Induced
- Hemoglobinuria, Paroxysmal
- Mitral Valve Stenosis