Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery.
case_report · Level V
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Abstract
Heparin is the standard agent used for systemic anticoagulation during cardiopulmonary bypass in cardiac operations. Alternatives are needed when patients with heparin-induced thrombocytopenia type II are encountered. We present a patient with a clinical picture of heparin-induced thrombocytopenia type II who was effectively anticoagulated with bivalirudin, a direct thrombin inhibitor, during cardiopulmonary bypass for a cardiac operation.
Medical subject headings
- Anticoagulants
- Cardiac Surgical Procedures
- Cardiopulmonary Bypass
- Hirudins
- Peptide Fragments
- Recombinant Proteins