Systemic-to-pulmonary artery shunt thrombosis in a neonate with factor V Leiden mutation.

Simsic, Janet M; Uber, Walter E; Lazarchick, John; Bradley, Scott M · Ann Thorac Surg · 2002

case_report · Level V

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Abstract

We present the case of a newborn male with D-transposition of the great arteries, ventricular septal defect, and subpulmonary stenosis who experienced two episodes of systemic-to-pulmonary artery shunt thrombosis. Hematologic evaluation revealed heterozygous factor V Leiden mutation. This report emphasizes the importance of evaluation for inherited coagulation disorders in pediatric patients with unexpected thrombotic complications.

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