Metrorrhagia and precocious puberty revealing primary hypothyroidism in a child with Down's syndrome.
case_report · Level V
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- Record sourced from PubMed, PMID 12651760.
- Also identified by PMC identifier 1719525.
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Abstract
We report a child with Down's syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can lead to this peculiar presentation.
Medical subject headings
- Down Syndrome
- Hypothyroidism
- Metrorrhagia
- Puberty, Precocious