Cerebral venous thrombosis: clinical outcome and systematic screening of prothrombotic factors.

Cakmak, S; Derex, L; Berruyer, M; Nighoghossian, N; Philippeau, F; Adeleine, P; Hermier, M; Froment, J C et al. · Neurology · 2003

case_series · Level IV

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Abstract

The authors studied 16 consecutive cases of cerebral venous thrombosis (CVT). Clinical outcome was good or excellent in 14 patients. Comprehensive hypercoagulable screening was done at least 3 months after the onset of CVT, including evaluation of genetic coagulation disorders and plasma levels of homocysteine and factor VIII. This screening was positive in 12 patients (75%). An acquired prothrombotic factor was identified in 9 of these 12 patients. Elevation of factor VIII plasma level was the most common coagulation disorder (8 patients).

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