Will endothelin receptor antagonists have a role in heart failure?
review · Level V
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- Record sourced from PubMed, PMID 12693734.
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Abstract
Mixed ET(A/B) and selective ET(A) receptor antagonists showed promising hemodynamic and symptomatic improvements in patients with heart failure. Randomized, clinical trials to investigate the effects of ET receptor antagonists on survival in patients with heart failure still need to be conducted. Also, the effects of selective ET(A) and mixed ET(A/B) receptor antagonists on the clinical outcome of patients with CHF will have to be assessed.
Medical subject headings
- Cardiovascular Agents
- Endothelin Receptor Antagonists
- Endothelins
- Heart Failure