Haemoglobin Marseille-Long Island and interpretation of HbA1c: which HbA1c result is the "right answer"?
case_report · Level V
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- Record sourced from PubMed, PMID 12697922.
- Also identified by PMC identifier 1742634.
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Abstract
A woman was screened for diabetes using glycated haemoglobin (HbA1c). Vastly different results were obtained by high performance liquid chromatography (45%), immunoassay (2.9%), and affinity chromatography (4.2%) compared with the non-diabetic range of less than 6.4%. Mass spectral studies confirmed the presence a haemoglobin variant, haemoglobin Marseille-Long Island which had confounded interpretation by all methods.
Medical subject headings
- Diabetes Mellitus
- Glycated Hemoglobin