The effect of clonidine on gastrointestinal side effects associated with ultra-rapid opioid detoxification.

Ma, Hong; Tang, Jun; White, Paul F; Wender, Ronald H; Leverone, Thomas; Quon, Rayond; Pearce, Scott; Chiao, Franklin et al. · Anesth Analg · 2003

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Abstract

Clonidine, an alpha(2)-adrenergic agonist, is used to minimize withdrawal symptoms related to ultra-rapid opioid detoxification procedures. These preliminary data suggest that clonidine possesses dose-related antidiarrheal activity.

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