Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy.
cross_sectional · Level IV
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Abstract
The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10 patients with ET and 10 volunteers using a multislice MR spectroscopy imaging sequence. Left and right cerebellar hemisphere NAA/CR and NAA/Cho ratios were significantly smaller in the ET patients than healthy subjects. The authors' data suggest that the decreased NAA/Cr and NAA/Cho ratios within the cerebellum may represent an abnormality in neuronal function.
Medical subject headings
- Aspartic Acid
- Cerebellum
- Essential Tremor
- Magnetic Resonance Spectroscopy