Fulminant adenovirus hepatitis following bone marrow transplantation. A case report and brief review of the literature.
case_report · Level V
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Abstract
Adenovirus infections are frequently encountered in immunocompromised patients and transplant recipients. However, fulminant hepatic failure due to adenovirus infection as a fatal complication in bone marrow transplant recipients is extremely rare. We report a case of fulminant adenovirus hepatitis in a 21-year-old allogeneic bone marrow transplant recipient who subsequently died of the disease. The diagnosis was established by histologic and immunohistochemical examination of a liver biopsy and was confirmed by liver tissue and blood cultures.
Medical subject headings
- Bone Marrow Transplantation
- Hepatic Encephalopathy
- Hepatitis, Viral, Human