Prenatal diagnosis by DNA polymorphism analysis of complete mole with coexisting twin.

Wax, Joseph R; Pinette, Michael G; Chard, Renée; Blackstone, Jacquelyn; Cartin, Angelina · Am J Obstet Gynecol · 2003

case_report · Level V

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Abstract

Partial mole is distinguishable from complete mole with coexisting normal twin after delivery by DNA polymorphysm analysis. Our patient had chorionic villus sampling of a molar-appearing placenta with coexisting fetus at 12.3 weeks. Absent maternal alleles confirmed a diandrogenetic complete mole. Prenatal DNA diagnosis of complete mole is possible and clinically useful.

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