HBV associated nephrotic syndrome: resolution with oral lamivudine.

Connor, F L; Rosenberg, A R; Kennedy, S E; Bohane, T D · Arch Dis Child · 2003

case_report · Level V

Where this comes from

Abstract

A 6 year old boy presenting with a five month history of fever, lethargy, and anorexia, was found to have hepatitis B associated membranous glomerulonephropathy and nephrotic syndrome. After two months treatment with oral lamivudine, his proteinuria cleared and serum albumin and aminotransferases normalised, associated with disappearance of hepatitis B e antigen (HBeAg) and appearance of anti-HBeAg antibodies. After 12 months, without side effects, lamivudine was discontinued. He remains well 11 months off treatment.

Medical subject headings