The Na/K pump, Cl ion, and osmotic stabilization of cells.
basic_science · Level V
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- Record sourced from PubMed, PMID 12730376.
- Also identified by PMC identifier 156359.
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Abstract
An equation for membrane voltage is derived that takes into account the electrogenicity of the Na/K pump and is valid dynamically, as well as in the steady state. This equation is incorporated into a model for the osmotic stabilization of cells. The results emphasize the role of the pump and membrane voltage in lowering internal Cl(-) concentration, thus making osmotic room for vital substances that must be sequestered in the cell.
Medical subject headings
- Cell Membrane Permeability
- Cell Physiological Phenomena
- Chlorides
- Muscle, Skeletal
- Sodium-Potassium-Exchanging ATPase