Treatment of nonatypical and atypical endometrial hyperplasia with a levonorgestrel-releasing intrauterine system.

Wildemeersch, D; Dhont, M · Am J Obstet Gynecol · 2003

case_series · Level IV

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Abstract

A "frameless" intrauterine drug delivery system that releases 14 microg/d of levonorgestrel was used to treat nonatypical and atypical endometrial hyperplasia in 12 women. This noncomparative study had up to 3 to 4 years of follow-up. The cure rate was 100%, as confirmed by repeat endometrial biopsy. This method could be considered an alternative to hysterectomy.

Medical subject headings