Functionally mature virus-specific CD8(+) T memory cells in congenitally infected newborns: proof of principle for neonatal vaccination?
review · Level V
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- Record sourced from PubMed, PMID 12782666.
- Also identified by PMC identifier 156114.
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Abstract
The presence in newborns of a mature and functional CD8(+) T cell response to congenital cytomegalovirus infection suggests that the machinery necessary to prime such responses is present in utero and raises questions related to neonatal vaccination.
Medical subject headings
- CD8-Positive T-Lymphocytes
- Immunization
- Immunologic Memory