The frequency of thrombotic thrombocytopenic purpura in patients with systemic lupus erythematosus undergoing kidney biopsy.

Manadan, Augustine M; Harris, Charlotte; Schwartz, Melvin M; Block, Joel A · J Rheumatol · 2003

case_report · Level V

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Abstract

To characterize the frequency of thrombotic thrombocytopenic purpura (TTP) among patients with systemic lupus erythematosus (SLE) undergoing kidney biopsy. A retrospective review of all renal biopsies of patients with SLE at Rush-Presbyterian-St. Luke's Medical Center was performed for the years 1989 to 2001. Four cases of clinical and histopathological TTP were identified among the 257 patients with SLE who underwent renal biopsy during the 12 year study period. TTP appears to occur at higher than expected frequency among SLE patients undergoing biopsy for unexplained renal failure.

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