Nanog: a new recruit to the embryonic stem cell orchestra.
review · Level V
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Abstract
In this issue of Cell, and add a new transcriptional operating system to the known Oct4 and Stat3 systems required for early embryonal stem cell potency and self-renewal. Nanog, a homeobox transcription factor, plays a crucial role in the second embryonic cell fate specification following formation of the blastocyst.
Medical subject headings
- Cell Differentiation
- Embryo, Mammalian
- Homeodomain Proteins
- Totipotent Stem Cells
- Transcription Factors