Non-24-hour sleep-wake syndrome following a car accident.
case_report · Level V
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- Record sourced from PubMed, PMID 12796546.
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Abstract
The authors report the case of a 39-year-old sighted woman who displayed non-24-hour sleep-wake cycles following a car accident. The phase relationship between endogenous circadian markers such as plasma melatonin and 6-sulfatoxymelatonin rhythms and self-selected sleep times was abnormal. A laboratory investigation indicated that she was sensitive to bright light as a circadian synchronizer. MRI and brain CT scans were normal, but microscopic brain damage in the vicinity of the suprachiasmatic nucleus or its output pathways is plausible.
Medical subject headings
- Accidents, Traffic
- Melatonin
- Sleep Disorders, Circadian Rhythm