Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations.

Fernandez, H; Bourget, P; Lelaidier, C; Doumerc, S; Frydman, R · Ultrasound Obstet Gynecol · 1993

case_report · Level V

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Abstract

We describe a case of spontaneous twin ectopic pregnancy, managed with the combination of local injection under ultrasound control and intramuscular administration of methotrexate. We describe a difference between the area under the curve of declining plasma concentration of methotrexate after intramuscular and local injection.