MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing.
review · Level V
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Abstract
Drosophila geneticists have uncovered roles for microRNAs in the coordination of cell proliferation and cell death during development, and in stress resistance and fat metabolism. In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing.
Medical subject headings
- Caenorhabditis elegans
- Drosophila melanogaster
- MicroRNAs
- RNA, Messenger