mRNA cap-1 methyltransferase in the SARS genome.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 12809601.
- Also identified by PMC identifier 7126025.
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Abstract
The 3D jury system has predicted the methyltransferase fold for the nsp13 protein of the SARS coronavirus. Based on the conservation of a characteristic tetrad of residues, the mRNA cap-1 methyltransferase function has been assigned to this protein, which has potential implications for antiviral therapy.
Medical subject headings
- Carrier Proteins
- Genome, Viral
- Methyltransferases
- RNA, Messenger
- Severe acute respiratory syndrome-related coronavirus
- Severe Acute Respiratory Syndrome
- Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
- Viral Proteins