Arginase: marker, effector, or candidate gene for asthma?

Vercelli, Donata · J Clin Invest · 2003

review · Level V

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Abstract

Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression, suggesting that arginine pathways are critical in the pathogenesis of asthma.

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