An eye on insulin.

Bronson, Sarah K; Reiter, Chad E N; Gardner, Thomas W · J Clin Invest · 2003

review · Level V

Where this comes from

Abstract

Diabetic retinopathy, the most frequent complication of diabetes and leading cause of vision loss, involves vascular and neural damage in the retina. Insulin and IGF-1 signaling are now shown to contribute to retinal neovascularization, in part, by modulating the expression of various vascular mediators.

Medical subject headings