Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival?
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Abstract
There is growing interest in more widespread application of isolated islet transplantation for the treatment of type 1 diabetes; however, the sequelae of long-term islet residence within the liver are unknown. We report herein a consequence of intraportal islet transplantation, specifically the development of periportal hepatic steatosis apparently induced by the local secretion of insulin within the liver.
Medical subject headings
- Graft Survival
- Islets of Langerhans Transplantation
- Liver
- Liver Diseases
- Magnetic Resonance Imaging
- Postoperative Complications