Binding of D-mannose to poly(2-hydroxyethyl methacrylate) hydrogels by azo coupling.
basic_science · Level V
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Abstract
Crosslinked hydrogels based on poly(2-hydroxyethyl methacrylate) poly(HEMA) were prepared and modified with tyramine [4-(2-aminoethyl)phenol] to enable azo coupling with mannosyl derivatives, copolymerization of HEMA with polymerizable activated esters and surface modification reaction with 4-nitrophenyl chlorocarbonate for activation of the hydrogels were used.
Medical subject headings
- Biocompatible Materials
- Hydrogels
- Mannose
- Nitrophenols
- Polyhydroxyethyl Methacrylate
- Tyramine