Biochemical indicator for evaluation of connective tissue abnormalities in Menkes' disease.

Kodama, Hiroko; Sato, Emi; Yanagawa, Yukisige; Ozawa, Hiroshi; Kozuma, Takamitsu · J Pediatr · 2003

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Abstract

Metabolites of collagen metabolism were analyzed in patients with Menkes' disease. The urinary deoxypyridinoline level was significantly low in the patients with Menkes' disease, indicating that it is a good marker of lysyl oxidase activity, which is related to the connective tissue abnormalities.

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