Pegylated interferon and ribavirin-induced interstitial pneumonitis with ARDS.
case_report · Level V
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- Record sourced from PubMed, PMID 12853555.
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Abstract
A 49-year-old man with cirrhosis due to hepatitis C virus developed interstitial pneumonitis documented by surgical lung biopsy specimen evaluation after two weekly doses of pegylated interferon-alpha(2)b in combination with ribavirin. He developed ARDS and died after 26 days of hospitalization from multisystem organ failure. This case suggests that interstitial pulmonary disease can occur with pegylated interferon-alpha(2)b therapy.
Medical subject headings
- Antiviral Agents
- Interferon-alpha
- Lung Diseases, Interstitial
- Polyethylene Glycols
- Respiratory Distress Syndrome
- Ribavirin