Olanzapine for intractable nausea in palliative care patients.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 12854942.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Nausea is a common problem among palliative care patients, which is often undertreated. Olanzapine, an atypical antipsychotic, possesses a unique neurotransmitter binding profile that is similar to methotrimeprazine, an anti-emetic widely used in Europe for recalcitrant nausea. We report a case series of six patients who suffered nausea which was resistant to initial treatment with traditional antiemetics; each patient exhibited marked improvement when treated with olanzapine.
Medical subject headings
- Antiemetics
- Nausea
- Palliative Care
- Pirenzepine