Alopecia areata and relapsing polychondritis or mosaic autoimmunity? The first experience of co-trimoxazole treatment.
case_report · Level V
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- Record sourced from PubMed, PMID 12860737.
- Also identified by PMC identifier 1754621.
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Abstract
A 13 year old girl presented with auricular chondritis and recurrent episodes of unexplained chest pain, arthritis, bronchitis, conjunctivitis, prolonged steroid resistant alopecia areata, and a history of recurrent tonsillitis. Both the mosaic of autoimmunity and relapsing polychondritis were considered in the differential diagnosis. The patient was successfully treated with co-trimoxazole. The significance of co-trimoxazole, which is an antibiotic and an immunomodulatory drug, in the treatment of autoimmune disease is discussed.
Medical subject headings
- Alopecia Areata
- Anti-Infective Agents
- Autoimmune Diseases
- Polychondritis, Relapsing
- Trimethoprim, Sulfamethoxazole Drug Combination