Ubiquitinated deiodinase: not dead yet.
review · Level V
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- Record sourced from PubMed, PMID 12865401.
- Also identified by PMC identifier 164296.
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Abstract
Originating in the thyroid, the prohormone thyroxine is converted to triiodothyronine, which is essential in brain development, growth, and metabolism. A study in this issue reveals a novel mechanism for controlling triiodothyronine production that provides the first example of enzyme activity being restored by deubiquitination.
Medical subject headings
- Iodide Peroxidase
- Thyroid Hormones
- Ubiquitin