Gene switching by metabolic enzymes--how did you get on the invitation list?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 12887915.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Histone gene expression in mammalian cells is codependent upon the Oct-1 transcription factor and its cognate, OCA-S coactivator complex. Surprisingly, GADPH plays an essential role in the OCA-S complex and confers redox dependence upon the in vitro transcription of histone genes.
Medical subject headings
- DNA-Binding Proteins
- Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+)
- Histones
- Trans-Activators
- Transcription Factors