Persistent subretinal indocyanine green induces retinal pigment epithelium atrophy.

Hirata, Akira; Inomata, Yasuya; Kawaji, Takahiro; Tanihara, Hidenobu · Am J Ophthalmol · 2003

case_report · Level V

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Abstract

To describe a case of a patient with macular hole with subretinal indocyanine green (ICG) during vitrectomy. Interventional case report. A 66-year-old woman with macular hole underwent a vitrectomy with ICG. After application of ICG into the vitreous, ICG was introduced in the subretinal space. Indocyanine green was found to be present for more than 6 months. Retinal pigment epithelium atrophy appeared at the site of the lesion. Although ICG may be a useful tool for distinguishing the internal limiting membrane and other tissues careful application is required to prevent side effects.

Medical subject headings